Dr. David Malkin

Senior Staff Oncologist,

Division of Haematology/Oncology

Sick Kids

Dr. Malkin is Professor of Pediatrics and Medical Biophysics in the Faculty of Medicine, University of Toronto. He holds the CIBC Children’s Foundation Chair in Child Health Research, is a Staff Oncologist in the Division of Hematology/Oncology, Director of the

Cancer Genetics program, and a Senior Scientist in the Genetics and Genome Biology Program at The Hospital for Sick Children in Toronto.

Dr. Malkin co-leads the SickKids Precision Child Health initiative. He co-directs the SickKids Cancer Sequencing (KiCS) program which integrates next generation sequencing (NGS) into clinical care of children with cancer, and Director of the pan-Canadian PRecision Oncology For Young peopLE (PROFYLE) initiative which is establishing a pipeline to incorporate NGS into novel clinical trials for children and young adults with hard-to-cure cancers across Canada. Dr. Malkin’s research focuses on genetic mechanisms of childhood cancer susceptibility particularly in the context of TP53 and Li-Fraumeni syndrome. Recently, his work has addressed the application of genomics to clinical surveillance and treatment approaches for children and adults at genetic ‘high risk’ for cancer.

Dr. Malkin’s research is funded by a variety of agencies and he has published over 300 peer-reviewed manuscripts. He has received numerous national and international awards recognizing his clinical, research and mentorship work, most recently being elected a Fellow of the Royal Society of Canada in 2022 and a Queen’s Platinum Jubilee Community Award in 2023.